Claude Opus 4.1 vs Mistral Large
Compare Claude Opus 4.1 by Anthropic against Mistral Large by Mistral AI, context windows of 200K vs 32K, tested across 14 shared challenges. Updated February 2026.
Compare Claude Opus 4.1 by Anthropic against Mistral Large by Mistral AI, context windows of 200K vs 32K, tested across 14 shared challenges. Updated February 2026.
14 challenges
Recreate an interactive, classic Mario level in a single HTML file.
Tests an AI's UI design skills with theming support
Generate a unique and simple recipe with common ingredients.
Create a starter plan for improving long-term health.
Recreate a classic, retro, macOS Desktop UI — make it interactive and nostalgic, make it as interactive as you can, you can be creative.. Feel free to showcase your skills. The entire application must be a single-page self-contained HTML file.
Develop a cutting-edge 3-month longevity plan for a biohacker.
This protocol integrates evidence-based interventions targeting the nine hallmarks of aging while optimizing immediate performance metrics. The approach follows a progressive adaptation model with built-in tracking and adjustment mechanisms.
Laboratory Markers:
Performance Baselines:
Morning Stack (with breakfast):
Afternoon Stack (with lunch):
Evening Stack (before bed):
Week 1: Standard Low-Carb Adaptation
Week 2: Ketogenic Transition
Meal Template:
First meal (12 PM): Protein-focused with vegetables
Second meal (6 PM): Fat-adapted dinner
Monday/Thursday: Strength Training (45 minutes)
Tuesday/Friday: Zone 2 Cardio
Wednesday: HIIT Protocol
Saturday: Active Recovery
Sunday: Rest
Cycling Protocol Introduction:
Senolytic Pulse (Last weekend of month):
Implement Protein Cycling:
Introduce Time-Restricted Feeding Variation:
Add Mitochondrial Support:
Nootropic Cycling (Workdays only):
Sleep Optimization Stack Enhancement:
Implement Cyclical Ketogenic Diet:
Fasting Escalation:
Nutrient Timing Optimization:
Strength Training Evolution (Monday/Wednesday/Friday):
HIIT Progression (Tuesday/Thursday):
Recovery Enhancement:
Morning HRV Protocol:
10% above baseline: High-intensity day
10% below: Recovery focus
Neurofeedback Training (3x/week):
Stress Inoculation:
Daily Monitoring:
Weekly Assessments:
Longevity Stack Additions:
Peptide Consideration (physician supervision):
NAD+ Optimization Cycling:
Implement Feast-Famine Cycling:
Fasting Mimicking Diet (Week 11):
Targeted Micronutrient Timing:
Implement Block Periodization:
Week 9-10: Strength/Power Block
Week 11: Deload/Recovery
Week 12: Testing Week
Advanced Recovery Protocols:
Nootropic Peak Stack (Week 9-10):
Brain Training Protocol:
Neurofeedback Advancement:
Advanced Sleep Architecture Enhancement:
Pre-sleep Protocol (2 hours before):
Sleep Stack (30 minutes before):
Sleep Environment:
Essential Wearables:
Data Integration Platform:
Key Performance Indicators:
Tier 1 (Essential, ~$200/month):
Tier 2 (Recommended, +$300/month):
Tier 3 (Optimal, +$500/month):
Medical Supervision Required For:
Contraindications to Consider:
Start Slow Principles:
This comprehensive protocol represents the cutting edge of biohacking for longevity. Remember that individual responses vary significantly, and what works for one person may not work for another. The key is systematic self-experimentation with careful tracking and adjustment.
Start with the fundamentals (sleep, nutrition, exercise, stress management) before adding advanced interventions. Build slowly, track meticulously, and always prioritize safety. The goal is not just to extend lifespan but to maximize healthspan—the years lived in optimal health and vitality.
Consider this protocol a template to be customized based on your genetics, lifestyle, goals, and response to interventions. The future of longevity is personalized, data-driven, and constantly evolving. Welcome to your optimization journey.
Optimized for Cellular Rejuvenation, Cognitive Enhancement, Physical Resilience, and Stress Adaptation
This 3-month protocol integrates cutting-edge biohacking strategies across nutrition, supplementation, exercise, recovery, cognitive enhancement, and stress resilience—all backed by peer-reviewed research, wearable tracking, and personalized adjustments.
The plan is structured in 3 phases (each 4 weeks), with progressive intensification in metabolic flexibility, mitochondrial efficiency, autophagy, and neuroplasticity.
Goal: Induce ketosis, enhance autophagy, stabilize blood glucose, and prime mitochondrial function while reducing inflammation.
| Supplement | Dosage | Timing | Purpose |
|---|---|---|---|
| NMN (Nicotinamide Mononucleotide) | 500mg | Morning | NAD+ booster, sirtuin activation |
| Resveratrol (Trans-Resveratrol) | 500mg | Morning | SIRT1 activator, antioxidant |
| Berberine | 500mg (3x/day) | Before meals | AMPK activator, glucose control |
| Magnesium L-Threonate | 2g | Evening | Cognitive function, synaptic plasticity |
| Omega-3 (EPA/DHA) | 2g (2:1 EPA:DHA) | With meals | Anti-inflammatory, brain health |
| Curcumin (Meriva or Longvida) | 1g | With meals | NF-κB inhibition, anti-inflammatory |
| Fisetin | 500mg | 2x/week | Senolytic (clears senescent cells) |
| Quercetin + Dasatinib | 500mg Quercetin + 50mg Dasatinib | 1x/week (Day 7) | Senolytic combo (consult physician) |
| Collagen Peptides | 10g | Morning | Skin, joint, gut integrity |
| Vitamin D3 + K2 (MK-7) | 5,000 IU D3 + 200mcg K2 | Morning | Bone, immune, cardiovascular health |
| Zinc Picolinate | 30mg | Evening | Immune, testosterone, antioxidant |
| Apigenin | 50mg | Evening | BDNF booster, anti-anxiety |
Goal: Enhance mitochondrial biogenesis, insulin sensitivity, and muscle protein synthesis while avoiding excessive cortisol.
| Day | Workout | Details | Recovery |
|---|---|---|---|
| Mon | Strength (Lower Body) | 5x5 Back Squat (80% 1RM), 4x6 Romanian Deadlift, 3x8 Bulgarian Split Squat | 10min cold shower post-workout |
| Tue | Zone 2 Cardio + Mobility | 60min cycling/walking (180-age HR), 15min yoga | 5min sauna (60°C) |
| Wed | HIIT (Metabolic Conditioning) | 10x (20s sprint / 40s walk), 4x12 Kettlebell Swings | 10min cold plunge (10°C) |
| Thu | Strength (Upper Body) | 5x5 Bench Press, 4x6 Weighted Pull-Ups, 3x8 Overhead Press | 5min sauna + 5min cold shower |
| Fri | Active Recovery (Blood Flow) | 30min swimming, 20min dynamic stretching | 20min infrared sauna |
| Sat | Long Slow Distance (LSD) | 90min hike or cycling (Zone 2) | 10min cold plunge |
| Sun | Rest or Yoga/Nidra | 30min yoga + 20min non-sleep deep rest (NSDR) | - |
| Metric | Tool | Target |
|---|---|---|
| Glucose Variability | CGM (Freestyle Libre) | <10% CV, fasting <85 mg/dL |
| Ketones | Keto-Mojo | 0.5-3.0 mmol/L (nutritional ketosis) |
| HRV | Whoop / Elite HRV | >70 (morning) |
| Sleep Score | Oura Ring / Whoop | >85 (deep sleep >20%) |
| Body Composition | DEXA Scan / InBody | <15% body fat (men), <22% (women) |
| Inflammation | Blood Test (hs-CRP, IL-6) | hs-CRP <1.0 mg/L |
Goal: Maximize mitochondrial efficiency, neuroplasticity, and metabolic flexibility while introducing hypoxic training and advanced nootropics.
| Supplement | Dosage | Timing | Purpose |
|---|---|---|---|
| NR (Nicotinamide Riboside) | 300mg | Morning | NAD+ precursor (alternate with NMN) |
| PQQ (Pyrroloquinoline Quinone) | 20mg | Morning | Mitochondrial biogenesis |
| Alpha-GPC | 300mg | Pre-workout | Choline source, cognitive enhancement |
| Lion’s Mane Mushroom | 1g | Morning | NGF (nerve growth factor) |
| Bacopa Monnieri | 300mg | Evening | Memory, BDNF |
| Rhodiola Rosea | 200mg | Morning (non-workout days) | Adaptogen, dopamine support |
| C60 (Carbon 60) | 5mg in MCT oil | Morning | Antioxidant, longevity |
| Urolithin A | 500mg | Morning | Mitophagy enhancer (from pomegranate) |
| Taurine | 2g | Post-workout | Mitochondrial protection, osmoregulation |
Goal: Enhance VO₂ max, lactate threshold, and power output while stimulating EPO and angiogenesis.
| Day | Workout | Details | Recovery |
|---|---|---|---|
| Mon | Strength (Lower) + Hypoxia | 5x5 Squat (85% 1RM), 4x6 Deadlift, 3x8 Jump Squats (breath holds) | 10min cold plunge |
| Tue | Zone 5 VO₂ Max Intervals | 6x (3min @90% max HR / 3min walk) | 20min sauna + 5min cold shower |
| Wed | Upper Body Hypertrophy | 4x8 Incline Bench, 4x8 Weighted Dips, 3x12 Face Pulls | 10min red light therapy |
| Thu | Hypoxic Endurance | 45min cycling (15% O₂ via mask or altitude training) | 10min cold plunge |
| Fri | Power & Explosiveness | 5x3 Power Cleans, 4x5 Box Jumps, 3x8 Kettlebell Snatches | 5min sauna |
| Sat | Long Zone 2 + Mobility | 90min hike (Zone 2) + 20min yoga | 20min infrared sauna |
| Sun | Active Recovery | 30min swimming + 10min breathwork | - |
| Metric | Tool | Target |
|---|---|---|
| VO₂ Max | Garmin / Whoop | >50 ml/kg/min (men), >45 (women) |
| Lactate Threshold | Blood Lactate Meter | >85% max HR |
| Cognitive Performance | Cambridge Brain Sciences | Top 20% in working memory, attention |
| Telomere Length | TeloYears Test | Above age-matched average |
| NAD+ Levels | Blood Test (Quest) | >30 µmol/L |
Goal: Optimize metabolic flexibility, cognitive resilience, and cellular repair while stress-testing adaptations.
| Supplement | Dosage | Timing | Purpose |
|---|---|---|---|
| NMN + NR (Alternating) | 500mg NMN or 300mg NR | Morning | NAD+ optimization |
| Metformin (if insulin resistant) | 500mg | Evening | AMPK activation (consult physician) |
| Rapamycin (Sirolimus) (Experimental) | 5mg | 1x/week | mTOR inhibition (consult physician) |
| Hyaluronic Acid | 100mg | Morning | Skin, joint, gut lining |
| Astaxanthin | 12mg | With meals | Antioxidant, UV protection |
| L-Theanine + Caffeine | 200mg L-Theanine + 100mg Caffeine | Morning | Focus, dopamine modulation |
| 5-HTP | 100mg | Evening | Serotonin precursor (if needed) |
Goal: Maximize strength, power, and endurance while stress-testing metabolic flexibility.
| Day | Workout | Details | Recovery |
|---|---|---|---|
| Mon | Max Strength (Lower) | 3x3 Back Squat (90% 1RM), 3x3 Deadlift, 3x5 Front Squat | 10min cold plunge |
| Tue | VO₂ Max + Hypoxia | 8x (1min @95% max HR / 2min walk) + 10min breath holds | 20min sauna + 5min cold shower |
| Wed | Upper Body Power | 5x3 Bench Press (90% 1RM), 4x5 Weighted Pull-Ups, 3x6 Overhead Press | 10min red light therapy |
| Thu | Metabolic Conditioning | EMOM 15min: 5 Power Cleans + 10 Burpees | 10min cold plunge |
| Fri | Endurance + Strength Hybrid | 5x (400m run + 10 Deadlifts) | 20min infrared sauna |
| Sat | Long Zone 2 + Mobility | 120min hike (Zone 2) + 30min yoga | 10min cold plunge |
| Sun | Active Recovery | 30min swimming + 20min breathwork | - |
| Metric | Tool | Target |
|---|---|---|
| Body Composition | DEXA Scan | <12% body fat (men), <20% (women) |
| VO₂ Max | Lab Test | >55 ml/kg/min (men), >50 (women) |
| Grip Strength | Dynamometer | >60kg (men), >40kg (women) |
| Cognitive Function | Cambridge Brain Sciences | Top 10% in working memory, attention |
| Inflammation (hs-CRP) | Blood Test | <0.5 mg/L |
| Telomere Length | TeloYears | Above 75th percentile for age |
To sustain gains, follow this maintenance protocol:
✅ Consult a physician before starting (especially for rapamycin, metformin, or senolytics). ✅ Listen to your body – adjust intensity if HRV drops or sleep suffers. ✅ Track biomarkers every 4 weeks to optimize dosing. ✅ Prioritize sleep – aim for 7-9 hours nightly (deep sleep >20%). ✅ Cold exposure & sauna – 10min cold plunge post-workout, 20min sauna 3x/week.
This 3-month plan is the most advanced, science-backed longevity protocol available—designed to reverse biological age, enhance cognitive function, and optimize physical performance.
Are you ready to biohack your way to peak longevity? 🚀
Design an innovative, multi-component dish worthy of a 3-star Michelin restaurant.
This dish explores the liminal space between land and sea, where morning coffee meets ocean depths. The unexpected marriage of coffee and hamachi represents the Japanese philosophy of ittaikan (一体感) - the sense of oneness between contrasting elements. Each component tells part of a story: dawn breaking over coastal waters, the minerality of ocean spray, and the earthiness of volcanic shores.
Ingredients:
Preparation:
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Preparation:
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Preparation:
Equipment Needed:
Assembly (per plate):
Using a dry brush, create an organic swoosh of coffee soil across the plate, incorporating all three textures for visual depth
Arrange 5 slices of hamachi in a flowing line, slightly overlapping, following the coffee soil's curve
Place 7-9 yuzu pearls asymmetrically around the hamachi using precision tweezers
Position 2-3 pieces of crystallized seaweed tuile vertically for height
Dot shiso oil in decreasing sizes (5, 3, and 1 drop) along the composition
Garnish with:
Finish with a light dusting of kombu powder over one section
Specialty Ingredients:
Yield: 6 servings
Prep Time: 48 hours (including aging)
Active Time: 4 hours
Difficulty: Advanced Professional
This dish embodies the precision, innovation, and storytelling expected at the three-star level, where each element contributes to a harmonious whole while challenging conventional flavor boundaries.
*Michelin 3-Star Dish: "Ocean’s Whisper & Earth’s Embrace" A symphony of contradictions—briny depths meet terranean warmth, where the ephemeral meets the eternal.
Conceptual Narrative: This dish is a meditation on duality—the fleeting and the enduring, the cold and the warm, the raw and the refined. Inspired by the Japanese concept of wabi-sabi (beauty in imperfection) and the Nordic tradition of foraging, it juxtaposes the pristine, almost alien purity of deep-sea ingredients with the earthy, fungal richness of the forest floor.
The star pairing: raw geoduck clam (a phallic, pulsating creature of the Pacific) with fermented black trumpet mushrooms (the "truffle of the poor," with a smoky, almost meaty depth). The clam, barely touched by heat, represents the ocean’s immediacy; the mushrooms, slow-fermented for months, embody time’s alchemy. A smoked eel consommé bridges the two, its umami depth echoing both sea and soil.
Visually, the dish is a landscape in miniature—a "beach" of toasted buckwheat and sea lettuce, a "tide pool" of geoduck ceviche, and a "forest" of mushroom tuiles and edible flowers. The plating is deliberately asymmetrical, with one side dominated by cool, wet textures (clam, cucumber, citrus) and the other by warm, dry elements (mushrooms, buckwheat, smoked oil).
(The "Tide Pool")
Ingredients (serves 4):
Technique: "Living Ceviche" (Sous-Vide Acid Denaturation)
Geoduck Preparation:
Sea Lettuce "Sand":
Assembly:
(The "Forest Floor")
Ingredients:
Smoked Eel Consommé:
Fermented Mushroom "Dirt":
Smoked Eel Consommé:
Assembly:
(The "Shore")
Ingredients:
Buckwheat "Sand":
Cucumber "Pebbles":
Assembly:
(The "Atmosphere")
Ingredients:
Smoked Oil:
Citrus Air:
Final Touch:
Final Thought: This dish is not just eaten—it’s experienced. It challenges the diner to reconsider texture, temperature, and time, all while delivering profound umami, acidity, and a haunting smokiness. The plating is deliberately unbalanced, forcing the eye to wander and the mind to engage. In a 3-star setting, it would be served as part of a 10-course tasting menu, preceded by a kelp-infused amuse-bouche and followed by a burnt honey and pine dessert.
Would you like a wine or non-alcoholic pairing suggestion to complete the experience?
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