3‑Month Longevity & Performance Blueprint
(Designed for an experienced biohacker who already has a baseline of health, fitness, and access to advanced tools. This is a general framework; always verify with a qualified health professional before making major changes.)
1. Overview & Core Objectives
| Goal | Target (Month 3) | Key Metrics |
|---|
| Physical Performance | ↑ 10 % VO₂max, ↑ 15 % 1‑RM in major lifts | Strength lift logs, VO₂max (or HR‑based estimate), body composition |
| Cognitive Function | ↑ 8 % on standardized memory/attention tests | Digit‑span, Stroop, Trail‑making |
| Longevity Biomarkers | ↓ Inflammatory markers, ↑ NAD⁺/NADH ratio | hs‑CRP, IL‑6, NAD⁺/NADH (if available) |
| Sleep & Recovery | 7‑8 h total, 80 % deep sleep | Oura/Apple Watch sleep stages |
| Stress Resilience | HRV (RMSSD) ≥ 50 ms in 24 h average | HRV, perceived stress scale |
| Metabolic Health | Fasting glucose ≤ 90 mg/dL, HbA1c ≤ 5.5 % | Blood glucose, HbA1c |
2. Tools & Wearables
| Device | Primary Data | Why It Matters |
|---|
| Oura Ring | HRV, sleep stages, body temperature, activity | Night‑time HRV & sleep quality |
| Apple Watch Series 9 / Whoop Strap | HR, HRV, VO₂max estimate, movement | Real‑time training load & recovery |
| NordicTrack or Peloton (or any high‑quality treadmill) | Power output, heart rate | Precise HIIT & strength training |
| Muse 2 Headband | EEG, heart rate, breathing | Neurofeedback & meditation coaching |
| Fitbit Sense | SpO₂, skin temperature, stress score | Additional stress & sleep metrics |
| Blood Glucose Meter (Freestyle Libre) | Capillary glucose | Fasting & post‑meal monitoring |
| Smart Scale (With body composition) | Lean mass, fat %, BMR | Tracking body composition changes |
Set up a simple dashboard (e.g., Notion or Google Sheets) to pull data weekly via API integrations. Keep a “Daily Log” for supplements, meals, sleep, and training.
3. Supplement Stack (Dosage & Cycling)
| Supplement | Dose (Daily) | Timing | Cycling | Rationale |
|---|
| Nicotinamide Mononucleotide (NMN) | 250 mg (split 125 mg AM/PM) | With meals | 6 weeks on / 2 weeks off | Boosts NAD⁺, supports mitochondrial health |
| Pyrroloquinoline Quinone (PQQ) | 10 mg | AM | 6 weeks on / 2 weeks off | Enhances biogenesis, antioxidant |
| Coenzyme Q10 (Ubiquinol) | 150 mg | PM | 6 weeks on / 2 weeks off | Supports electron transport chain |
| Resveratrol | 150 mg | AM | 4 weeks on / 1 week off | Activates SIRT1, anti‑inflammatory |
| Curcumin (with piperine) | 500 mg curcumin + 5 mg piperine | AM | 4 weeks on / 1 week off | Anti‑oxidant, reduces IL‑6 |
| Berberine | 500 mg | AM | 4 weeks on / 1 week off | Improves insulin sensitivity |
| Alpha‑Lipoic Acid (ALA) | 300 mg | AM | 4 weeks on / 1 week off | Regenerates other antioxidants |
| Vitamin D₃ | 5 000 IU | PM | Daily | Supports immune & bone health |
| Magnesium Threonate | 400 mg | PM | Daily | Enhances sleep & neuronal function |
| Omega‑3 (EPA/DHA 2:1) | 2 g total | PM | Daily | Anti‑inflammatory, brain health |
| Zinc (Picolinate) | 30 mg | PM | Daily | Immune support, enzyme function |
| Nicotinamide (Vitamin B3) | 500 mg | AM | Daily | Supports NAD⁺ synthesis |
| Quercetin | 500 mg | AM | 4 weeks on / 1 week off | Antioxidant, stabilizes mast cells |
| Ashwagandha (root extract) | 600 mg | PM | 6 weeks on / 2 weeks off | Adaptogen, reduces cortisol |
| Rhodiola Rosea | 200 mg | AM | 4 weeks on / 1 week off | Enhances endurance & cognition |
| N‑Acetylcysteine (NAC) | 600 mg | PM | 4 weeks on / 1 week off | Glutathione precursor |
Cycling Tips
- Rotate “on/off” periods weekly (e.g., Week 1‑6 on, Week 7‑8 off).
- Keep a simple spreadsheet to track when each supplement is paused.
- If you’re taking prescription meds, consult a professional before adding any of the above.
4. Dietary Protocols
4.1 Macronutrient Targets
| Macro | % of Total Calories | Example (2 200 kcal) |
|---|
| Protein | 25 % (≈ 138 g) | Chicken, fish, tofu, whey isolate |
| Fat | 55 % (≈ 134 g) | Avocado, coconut oil, MCT oil, nuts |
| Carbs | 20 % (≈ 110 g) | Low‑glycemic veggies, berries (if keto‑flexible) |
4.2 Ketogenic Variations
| Variation | When to Use | Key Features |
|---|
| Standard Keto | 3‑4 days/week | < 20 g net carbs/day |
| Targeted Keto (TK) | 2 days/week (post‑workout) | 30‑50 g carbs 30 min after HIIT |
| Cyclical Keto (CK) | 1 day/week (re‑feed) | 100‑150 g carbs, focus on legumes & starchy veg |
4.3 Fasting Regimens
| Regimen | Schedule | Notes |
|---|
| 16:8 | Fast 16 h (e.g., 8 pm‑12 pm) | Easy to maintain, best for insulin sensitivity |
| 24‑h Fast | 2×/week (e.g., Monday & Thursday) | Can be done from dinner to dinner; stay hydrated |
| 5:2 | 2×/week low‑calorie (600 kcal) | Alternative to full 24‑h fast |
4.4 Sample Meal Plan (Standard Keto, 16:8)
| Meal | Time | Foods | Calories |
|---|
| Breakfast (Lunch) | 12 pm | 2 eggs scrambled in butter, ½ avocado, 1 cup spinach sautéed in coconut oil | 600 |
| Snack | 3 pm | 30 g mixed nuts + 1 oz cheese | 250 |
| Dinner | 6 pm | 8 oz salmon, 2 cups broccoli roasted in olive oil, 1 tbsp butter | 700 |
| Post‑Workout (if TK) | 7 pm | 1 cup cooked quinoa + 1 tbsp almond butter | 300 |
| Total | | | 2 200 |
Adjust portions to hit your caloric target. Keep a log of net carbs (total carbs – fiber) to stay within 20 g on keto days.
4.5 Food Quality & Timing
- Protein: Prioritize grass‑fed, pasture‑raised, or wild‑caught.
- Fats: Use MCT oil (1 tsp) in coffee or smoothies for quick energy.
- Veggies: Aim for 3‑4 cups of non‑starchy veg daily.
- Hydration: 3 L water + electrolytes (NaCl, KCl) during fasts.
- Supplement Timing: Take NMN, PQQ, CoQ10, and resveratrol with meals; magnesium and sleep‑supporting supplements in the evening.
5. Exercise & Recovery Blueprint
5.1 Weekly Structure
| Day | Focus | Session | Duration | Notes |
|---|
| Mon | Strength (Upper) | 3 sets × 6‑8 reps (bench press, rows) | 60 min | Progressive overload |
| Tue | HIIT + Mobility | 20 min Tabata (30 s sprint / 10 s walk) + 15 min mobility flow | 35 min | HRV check pre‑post |
| Wed | Strength (Lower) | 3 sets × 6‑8 reps (squat, deadlift) | 60 min | Use a 1‑RM test every 4 weeks |
| Thu | Active Recovery | Light swim or yoga | 45 min | Focus on breathing |
| Fri | Strength (Full‑Body) | Compound circuit (clean & press, pull‑ups) | 45 min | Keep RPE ≤ 7 |
| Sat | HIIT + Sprint Ladder | 30 min (incl. hill sprints) | 30 min | Post‑workout NMN + PQQ |
| Sun | Rest | No structured activity | — | Sleep hygiene & journaling |
5.2 Strength Training Details
- Load: Start at 70 % 1‑RM, increase by 2.5 % each week.
- Rest: 2‑3 min between sets for hypertrophy, 4‑5 min for maximal strength.
- Tracking: Log weight, reps, perceived exertion (RPE) in your dashboard.
- Periodization: Weeks 1‑4 (hypertrophy), 5‑7 (strength), 8‑12 (power).
5.3 HIIT Protocol
| Interval | Effort | Rest |
|---|
| 30 s | 90 % max HR (or 8‑10 on RPE) | 10 s walk |
| Repeat 8× | 4 min cool‑down | 5 min dynamic stretch |
Use a treadmill or stationary bike for precise HR monitoring.
5.4 Recovery & Regeneration
- Foam Rolling: 10 min post‑workout.
- Stretching: 15 min static stretch focusing on hamstrings, quadriceps, shoulders.
- Cold Exposure: 5‑10 min ice bath or cold shower after HIIT (once/week).
- Sauna: 15‑20 min infrared sauna (2×/week).
- Sleep: Aim for 7‑8 h; use Oura to track sleep stages.
6. Stress Resilience & Cognitive Enhancement
| Technique | Frequency | Tool | How It Works |
|---|
| HRV‑Based Breathing | Daily (5 min) | Apple Watch or Elite HRV app | 4‑7‑8 breathing pattern to increase parasympathetic tone |
| Meditation (Mindfulness) | 10 min before bed | Insight Timer or Headspace | Improves focus, reduces cortisol |
| Neurofeedback (DIY) | 2×/week | Muse 2 Headband (guided sessions) | Trains alpha‑wave activity, reduces mind‑wandering |
| Progressive Muscle Relaxation | Evening (5 min) | Guided audio | Lowers sympathetic activity |
| Journaling (Gratitude + Stress Log) | Daily | Notion template | Enhances emotional regulation |
| Blue‑Light Blocking | Evening | Night‑mode on devices + blue‑light glasses | Improves melatonin production |
HRV Check‑In
- Morning: Record RMSSD; aim for ≥ 50 ms.
- Evening: If RMSSD < 40 ms, add an extra 5 min breathing session or a short walk.
7. Environmental & Lifestyle Optimizations
| Area | Action | Benefit |
|---|
| Light Exposure | 30 min bright light (≥ 10 000 lux) in the morning; dim lights after 7 pm | Aligns circadian rhythm |
| Temperature | Keep bedroom 60‑65 °F (15‑18 °C) | Enhances deep sleep |
| Air Quality | HEPA filter, 1×/week deep clean | Reduces oxidative stress |
| Social Interaction | 2 hrs/week meaningful conversation | Improves mental health |
| Digital Detox | No screens 1 h before bed | Better sleep quality |
8. Weekly Review & Adjustments
- Data Pull: Export Oura, Apple Watch, and sleep metrics.
- Performance Check: Compare strength lifts, VO₂max estimate, and HRV trends.
- Biomarker Review: If you have lab results (e.g., hs‑CRP, fasting glucose), note changes.
- Supplement Cycle: Decide if you’ll pause or continue based on how you feel.
- Diet Audit: Log net carbs, calories, and any deviations.
- Adjustments:
- Increase protein by 5 g if strength stalls.
- Add 5 min mobility if soreness > 2 days.
- Modify fasting window if sleep quality drops.
Monthly Milestone (End of Month 3)
- Strength: 10 % increase in 1‑RM (bench, squat, deadlift).
- Cardio: 5 % increase in VO₂max estimate.
- Sleep: ≥ 80 % deep sleep in Oura.
- HRV: Average RMSSD ≥ 60 ms.
- Biomarkers: hs‑CRP < 1 mg/L, fasting glucose ≤ 90 mg/dL.
9. Quick‑Start Checklist (Day 1)
| ✅ | Item |
|---|
| 1 | Set up Oura, Apple Watch, Muse 2, and Notion dashboard. |
| 2 | Order supplements (NMN, PQQ, CoQ10, Resveratrol, Curcumin, etc.). |
| 3 | Create a 7‑day meal plan with macros and grocery list. |
| 4 | Schedule first strength session (Upper) and HIIT session. |
| 5 | Begin 16:8 fasting (fast 8 pm‑12 pm). |
| 6 | Install Elite HRV app for daily HRV tracking. |
| 7 | Plan a 5‑minute breathing routine for morning and evening. |
Final Note
This plan is a high‑intensity, data‑driven roadmap. Listen to your body—if you experience persistent fatigue, joint pain, or any adverse symptoms, pause the protocol and consult a qualified professional. Keep a journal of subjective experiences; the qualitative data is just as valuable as the quantitative metrics. Good luck, and enjoy the journey toward optimal longevity and performance!