Ethical Dilemma with Stakeholders
You're the CEO of a pharmaceutical company. Your best-selling drug ($2B annual revenue, used by 4 million patients for chronic pain) has…
Decision: Do not wait. I disclose now. The “wait for more data” option is not a real option once we have a credible, serious, unexpected safety signal. Waiting 6 months would mean knowingly continuing to expose 4 million patients to a risk we already know about, while also creating far worse legal, regulatory, and…Read the full answer
As CEO, my overriding duty is to balance patient safety, legal/regulatory compliance, fiduciary responsibility, and long-term corporate survival. A 1-in-8,000 risk of liver failure is rare but severe, potentially fatal, and materially unexpected relative to the current label.Read the full answer